Tanzania Development and AIDS Prevention (TADEPA) is a local Non-Governmental Organization (NGO) that was registered in 1997 according to the Trustees Incorporation Ordinance (1956) with a certificate of compliance of June 2005 as per NGO act of 2002 based in Bukoba, Kagera Region, Tanzania.

TADEPA was initiated by former staff of Medecins du Monde (MDM) France; an international NGO. MDM started working in the Kagera region in 1992, focusing on HIV/AIDS interventions.

In 1997 the local staff decided to develop their work portfolio autonomously from MDM to take over the services that were initiated by MDM, a move fully supported by MDM, as it enabled local people and the local community to take ownership and enhance the sustainability of the programmes.

Following a phase out period, TADEPA was fully independent in 2001 and MDM withdrew from the program.